Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 04/08/2018 | Wycombe | 0 | 0 | Blackpool | N Kinseley |
| 11/08/2018 | Doncaster | 3 | 0 | Wycombe | C Boyeson |
| 18/08/2018 | Wycombe | 1 | 2 | Bristol Rvs | K Johnson |
| 21/08/2018 | Plymouth | 1 | 1 | Wycombe | O Yates |
| 25/08/2018 | Bradford | 1 | 2 | Wycombe | M Heywood |
| 01/09/2018 | Wycombe | 1 | 1 | Luton | D England |
| 08/09/2018 | Charlton | 3 | 2 | Wycombe | G Salisbury |
| 15/09/2018 | Wycombe | 0 | 0 | Oxford | D Webb |
| 22/09/2018 | Portsmouth | 2 | 2 | Wycombe | C Hicks |
| 29/09/2018 | Wycombe | 2 | 3 | Southend | T Nield |
| 02/10/2018 | Fleetwood Town | 1 | 1 | Wycombe | S Oldham |
| 06/10/2018 | Wycombe | 2 | 1 | Burton | C Breakspear |
| 13/10/2018 | Coventry | 1 | 0 | Wycombe | N Kinseley |
| 20/10/2018 | Wycombe | 3 | 2 | Scunthorpe | A Young |
| 23/10/2018 | Wycombe | 3 | 0 | Rochdale | B Huxtable |
| 27/10/2018 | Walsall | 3 | 2 | Wycombe | N Hair |
| 03/11/2018 | Wycombe | 1 | 0 | Peterboro | B Toner |
| 17/11/2018 | Sunderland | 1 | 1 | Wycombe | M Salisbury |
| 24/11/2018 | Wycombe | 3 | 2 | Shrewsbury | A Haines |
| 27/11/2018 | Accrington | 1 | 2 | Wycombe | S Oldham |
| 08/12/2018 | Wycombe | 1 | 0 | Barnsley | A Coggins |
| 15/12/2018 | Gillingham | 2 | 2 | Wycombe | D Whitestone |
| 22/12/2018 | Wycombe | 1 | 2 | AFC Wimbledon | J Busby |
| 26/12/2018 | Burton | 3 | 1 | Wycombe | M Salisbury |
| 29/12/2018 | Scunthorpe | 1 | 0 | Wycombe | D Drysdale |
| 01/01/2019 | Wycombe | 0 | 2 | Coventry | L Collins |
| 12/01/2019 | Wycombe | 3 | 2 | Doncaster | T Kettle |
| 19/01/2019 | Bristol Rvs | 0 | 1 | Wycombe | B Toner |
| 26/01/2019 | Wycombe | 1 | 0 | Plymouth | S Oldham |
| 29/01/2019 | Blackpool | 2 | 2 | Wycombe | M Coy |
| 02/02/2019 | Wycombe | 0 | 0 | Bradford | T Bramall |
| 09/02/2019 | Luton | 3 | 0 | Wycombe | A Davies |
| 16/02/2019 | Barnsley | 2 | 1 | Wycombe | M Donohue |
| 23/02/2019 | Wycombe | 0 | 1 | Gillingham | C Boyeson |
| 02/03/2019 | Peterboro | 4 | 2 | Wycombe | S Stockbridge |
| 09/03/2019 | Wycombe | 1 | 1 | Sunderland | L Swabey |
| 12/03/2019 | Wycombe | 1 | 3 | Accrington | K Johnson |
| 16/03/2019 | Shrewsbury | 2 | 1 | Wycombe | T Kettle |
| 30/03/2019 | Oxford | 2 | 1 | Wycombe | S Hooper |
| 06/04/2019 | Wycombe | 2 | 3 | Portsmouth | J Busby |
| 09/04/2019 | Wycombe | 0 | 1 | Charlton | A Coggins |
| 13/04/2019 | Southend | 0 | 2 | Wycombe | D Coote |
| 19/04/2019 | Rochdale | 1 | 0 | Wycombe | A Haines |
| 22/04/2019 | Wycombe | 1 | 0 | Walsall | C Breakspear |
| 27/04/2019 | AFC Wimbledon | 2 | 1 | Wycombe | A Davies |
| 04/05/2019 | Wycombe | 1 | 0 | Fleetwood Town | L Swabey |