Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 05/08/2017 | Wycombe | 2 | 2 | Lincoln | G Horwood |
| 12/08/2017 | Port Vale | 2 | 3 | Wycombe | C Hicks |
| 19/08/2017 | Wycombe | 2 | 4 | Notts County | G Salisbury |
| 26/08/2017 | Grimsby | 2 | 3 | Wycombe | M Heywood |
| 02/09/2017 | Wycombe | 3 | 1 | Forest Green | S Oldham |
| 09/09/2017 | Newport County | 0 | 0 | Wycombe | B Toner |
| 12/09/2017 | Mansfield | 0 | 0 | Wycombe | R Lewis |
| 16/09/2017 | Wycombe | 1 | 2 | Luton | J Linington |
| 23/09/2017 | Colchester | 1 | 2 | Wycombe | B Huxtable |
| 26/09/2017 | Wycombe | 3 | 2 | Crewe | A Haines |
| 30/09/2017 | Wycombe | 3 | 1 | Barnet | R Joyce |
| 07/10/2017 | Cambridge | 1 | 3 | Wycombe | G Ward |
| 14/10/2017 | Wycombe | 0 | 0 | Exeter | R Jones |
| 17/10/2017 | Carlisle | 3 | 3 | Wycombe | S Duncan |
| 21/10/2017 | Swindon | 1 | 0 | Wycombe | J Brooks |
| 28/10/2017 | Wycombe | 3 | 3 | Cheltenham | L Collins |
| 11/11/2017 | Morecambe | 2 | 1 | Wycombe | A Haines |
| 18/11/2017 | Wycombe | 4 | 0 | Crawley Town | A Coggins |
| 21/11/2017 | Accrington | 1 | 0 | Wycombe | R Joyce |
| 25/11/2017 | Wycombe | 2 | 1 | Yeovil | T Nield |
| 09/12/2017 | Stevenage | 0 | 0 | Wycombe | S Duncan |
| 16/12/2017 | Wycombe | 1 | 0 | Chesterfield | N Kinseley |
| 22/12/2017 | Coventry | 3 | 2 | Wycombe | T Harrington |
| 26/12/2017 | Wycombe | 2 | 0 | Newport County | C Breakspear |
| 30/12/2017 | Wycombe | 1 | 2 | Mansfield | C Sarginson |
| 01/01/2018 | Forest Green | 1 | 2 | Wycombe | A Coggins |
| 13/01/2018 | Wycombe | 3 | 1 | Colchester | J Busby |
| 20/01/2018 | Crewe | 2 | 3 | Wycombe | M Coy |
| 30/01/2018 | Luton | 2 | 3 | Wycombe | T Robinson |
| 03/02/2018 | Wycombe | 4 | 3 | Carlisle | C Boyeson |
| 10/02/2018 | Exeter | 1 | 1 | Wycombe | S Martin |
| 13/02/2018 | Wycombe | 3 | 2 | Swindon | A Madley |
| 17/02/2018 | Cheltenham | 0 | 2 | Wycombe | G Ward |
| 24/02/2018 | Wycombe | 2 | 4 | Morecambe | C Hicks |
| 27/02/2018 | Wycombe | 0 | 1 | Coventry | B Malone |
| 10/03/2018 | Wycombe | 1 | 1 | Cambridge | N Kinseley |
| 17/03/2018 | Barnet | 0 | 2 | Wycombe | L Collins |
| 21/03/2018 | Crawley Town | 2 | 3 | Wycombe | G Horwood |
| 24/03/2018 | Wycombe | 0 | 0 | Port Vale | L Swabey |
| 30/03/2018 | Notts County | 0 | 0 | Wycombe | B Toner |
| 02/04/2018 | Wycombe | 2 | 1 | Grimsby | C Sarginson |
| 14/04/2018 | Yeovil | 0 | 1 | Wycombe | G Ward |
| 17/04/2018 | Lincoln | 0 | 0 | Wycombe | J Brooks |
| 21/04/2018 | Wycombe | 0 | 4 | Accrington | D Drysdale |
| 28/04/2018 | Chesterfield | 1 | 2 | Wycombe | A Backhouse |
| 05/05/2018 | Wycombe | 1 | 0 | Stevenage | M Coy |