Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 07/08/2010 | Wycombe | 2 | 0 | Morecambe | R Lewis |
| 14/08/2010 | Morecambe | 0 | 0 | Rotherham | D Webb |
| 21/08/2010 | Burton | 3 | 2 | Morecambe | G Sutton |
| 28/08/2010 | Morecambe | 1 | 1 | Gillingham | M Brown |
| 04/09/2010 | Oxford | 4 | 0 | Morecambe | B Malone |
| 11/09/2010 | Morecambe | 1 | 1 | Chesterfield | A Bates |
| 18/09/2010 | Southend | 2 | 3 | Morecambe | M Russell |
| 25/09/2010 | Morecambe | 2 | 2 | Barnet | D Coote |
| 28/09/2010 | Morecambe | 1 | 4 | Bury | M Haywood |
| 02/10/2010 | Bradford | 0 | 1 | Morecambe | S Mathieson |
| 09/10/2010 | Morecambe | 1 | 0 | Shrewsbury | D Foster |
| 16/10/2010 | Aldershot | 2 | 1 | Morecambe | K Wright |
| 23/10/2010 | Morecambe | 0 | 0 | Stevenage | F Graham |
| 30/10/2010 | Torquay | 3 | 1 | Morecambe | P Gibbs |
| 02/11/2010 | Morecambe | 5 | 0 | Stockport | G Eltringham |
| 13/11/2010 | Morecambe | 1 | 2 | Lincoln | N Miller |
| 20/11/2010 | Cheltenham | 1 | 1 | Morecambe | D Sheldrake |
| 27/11/2010 | Morecambe | 1 | 2 | Crewe | D Drysdale |
| 11/12/2010 | Morecambe | 1 | 0 | Port Vale | R Shoebridge |
| 01/01/2011 | Morecambe | 1 | 2 | Accrington | S Mathieson |
| 03/01/2011 | Stockport | 0 | 2 | Morecambe | K Evans |
| 08/01/2011 | Shrewsbury | 1 | 3 | Morecambe | M Brown |
| 15/01/2011 | Morecambe | 2 | 1 | Torquay | A Woolmer |
| 22/01/2011 | Stevenage | 2 | 0 | Morecambe | D Whitestone |
| 25/01/2011 | Hereford | 2 | 1 | Morecambe | P Miller |
| 01/02/2011 | Accrington | 1 | 1 | Morecambe | J Moss |
| 05/02/2011 | Morecambe | 1 | 1 | Cheltenham | S Martin |
| 08/02/2011 | Morecambe | 1 | 1 | Aldershot | P Quinn |
| 12/02/2011 | Lincoln | 2 | 0 | Morecambe | G Scott |
| 15/02/2011 | Northampton | 3 | 3 | Morecambe | R Madley |
| 19/02/2011 | Morecambe | 0 | 3 | Oxford | P Gibbs |
| 22/02/2011 | Macclesfield | 2 | 0 | Morecambe | G Sutton |
| 26/02/2011 | Chesterfield | 0 | 2 | Morecambe | B Malone |
| 05/03/2011 | Morecambe | 2 | 1 | Southend | C Sarginson |
| 08/03/2011 | Bury | 1 | 0 | Morecambe | P Tierney |
| 12/03/2011 | Morecambe | 0 | 1 | Bradford | N Miller |
| 19/03/2011 | Barnet | 1 | 2 | Morecambe | M Naylor |
| 22/03/2011 | Morecambe | 1 | 2 | Macclesfield | J Moss |
| 26/03/2011 | Morecambe | 0 | 3 | Wycombe | T Kettle |
| 02/04/2011 | Rotherham | 0 | 1 | Morecambe | S Rushton |
| 09/04/2011 | Morecambe | 2 | 1 | Burton | K Evans |
| 16/04/2011 | Gillingham | 1 | 1 | Morecambe | D McDermid |
| 22/04/2011 | Crewe | 2 | 1 | Morecambe | C Sarginson |
| 25/04/2011 | Morecambe | 1 | 1 | Hereford | M Haywood |
| 30/04/2011 | Port Vale | 7 | 2 | Morecambe | R Lewis |
| 07/05/2011 | Morecambe | 1 | 2 | Northampton | A Haines |