Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 09/08/2014 | Cambridge | 1 | 0 | Plymouth | G Scott |
| 16/08/2014 | Portsmouth | 2 | 1 | Cambridge | D Sheldrake |
| 19/08/2014 | York | 2 | 2 | Cambridge | R Clark |
| 23/08/2014 | Cambridge | 1 | 2 | Morecambe | C Breakspear |
| 30/08/2014 | Cambridge | 5 | 0 | Carlisle | C Berry |
| 08/09/2014 | Newport County | 1 | 1 | Cambridge | S Martin |
| 13/09/2014 | Dag and Red | 2 | 3 | Cambridge | A Woolmer |
| 16/09/2014 | Cambridge | 1 | 2 | Exeter | D Drysdale |
| 20/09/2014 | Cambridge | 0 | 1 | Luton | G Salisbury |
| 27/09/2014 | Wycombe | 1 | 0 | Cambridge | D Handley |
| 03/10/2014 | Burton | 1 | 3 | Cambridge | M Russell |
| 11/10/2014 | Cambridge | 5 | 1 | Oxford | A D'Urso |
| 18/10/2014 | Mansfield | 0 | 0 | Cambridge | M Heywood |
| 21/10/2014 | Cambridge | 1 | 2 | Cheltenham | P Miller |
| 25/10/2014 | Cambridge | 2 | 1 | Hartlepool | K Johnson |
| 01/11/2014 | Bury | 2 | 0 | Cambridge | G Horwood |
| 14/11/2014 | Cambridge | 2 | 1 | Northampton | T Kettle |
| 22/11/2014 | Accrington | 2 | 1 | Cambridge | R Clark |
| 29/11/2014 | AFC Wimbledon | 1 | 2 | Cambridge | M Bull |
| 13/12/2014 | Cambridge | 0 | 0 | Shrewsbury | T Robinson |
| 19/12/2014 | Tranmere | 1 | 1 | Cambridge | D Handley |
| 26/12/2014 | Cambridge | 0 | 1 | Southend | O Langford |
| 28/12/2014 | Stevenage | 3 | 2 | Cambridge | F Graham |
| 10/01/2015 | Carlisle | 0 | 1 | Cambridge | M Heywood |
| 17/01/2015 | Cambridge | 4 | 0 | Newport County | S Attwell |
| 27/01/2015 | Cambridge | 1 | 1 | Dag and Red | G Sutton |
| 31/01/2015 | Luton | 3 | 2 | Cambridge | J Simpson |
| 07/02/2015 | Cambridge | 0 | 1 | Wycombe | A Davies |
| 10/02/2015 | Exeter | 2 | 2 | Cambridge | M Russell |
| 14/02/2015 | Plymouth | 2 | 0 | Cambridge | I Williamson |
| 21/02/2015 | Cambridge | 2 | 6 | Portsmouth | S Stockbridge |
| 24/02/2015 | Cambridge | 0 | 0 | AFC Wimbledon | G Ward |
| 28/02/2015 | Morecambe | 0 | 2 | Cambridge | D Handley |
| 03/03/2015 | Cambridge | 0 | 3 | York | A Woolmer |
| 07/03/2015 | Shrewsbury | 1 | 1 | Cambridge | M Bull |
| 14/03/2015 | Cambridge | 1 | 1 | Stevenage | G Horwood |
| 17/03/2015 | Cambridge | 1 | 2 | Tranmere | K Stroud |
| 21/03/2015 | Southend | 0 | 0 | Cambridge | B Malone |
| 28/03/2015 | Hartlepool | 2 | 1 | Cambridge | A Haines |
| 03/04/2015 | Cambridge | 0 | 2 | Bury | M Brown |
| 06/04/2015 | Northampton | 0 | 1 | Cambridge | F Graham |
| 11/04/2015 | Cambridge | 2 | 2 | Accrington | C Sarginson |
| 14/04/2015 | Cheltenham | 3 | 1 | Cambridge | G Sutton |
| 18/04/2015 | Cambridge | 3 | 1 | Mansfield | K Wright |
| 25/04/2015 | Oxford | 2 | 0 | Cambridge | C Berry |
| 02/05/2015 | Cambridge | 2 | 3 | Burton | O Langford |