Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 07/08/2010 | Swindon | 1 | 2 | Brighton | D Whitestone |
| 14/08/2010 | Brighton | 2 | 2 | Rochdale | D McDermid |
| 21/08/2010 | Sheffield Weds | 1 | 0 | Brighton | A Woolmer |
| 28/08/2010 | Brighton | 2 | 1 | Walsall | G Horwood |
| 11/09/2010 | Brighton | 2 | 0 | Milton Keynes Dons | P Gibbs |
| 18/09/2010 | Carlisle | 0 | 0 | Brighton | J Waugh |
| 21/09/2010 | Plymouth | 0 | 2 | Brighton | B Malone |
| 25/09/2010 | Brighton | 2 | 1 | Oldham | A Penn |
| 28/09/2010 | Brighton | 1 | 0 | Brentford | G Ward |
| 02/10/2010 | Tranmere | 1 | 1 | Brighton | N Miller |
| 09/10/2010 | Brighton | 1 | 1 | Bournemouth | D Sheldrake |
| 16/10/2010 | Charlton | 0 | 4 | Brighton | N Swarbrick |
| 23/10/2010 | Brighton | 2 | 0 | Yeovil | P Crossley |
| 30/10/2010 | Peterboro | 0 | 3 | Brighton | G Sutton |
| 02/11/2010 | Brighton | 3 | 0 | Exeter | K Hill |
| 13/11/2010 | Hartlepool | 3 | 1 | Brighton | R Booth |
| 20/11/2010 | Brighton | 2 | 2 | Bristol Rvs | K Stroud |
| 23/11/2010 | Southampton | 0 | 0 | Brighton | I Williamson |
| 11/12/2010 | Huddersfield | 2 | 1 | Brighton | A Haines |
| 29/12/2010 | Brighton | 1 | 1 | Charlton | D Deadman |
| 01/01/2011 | Brighton | 5 | 0 | Leyton Orient | J Linington |
| 03/01/2011 | Exeter | 1 | 2 | Brighton | S Tanner |
| 15/01/2011 | Brighton | 3 | 1 | Peterboro | B Malone |
| 22/01/2011 | Bournemouth | 1 | 0 | Brighton | K Hill |
| 25/01/2011 | Brighton | 2 | 0 | Colchester | G Scott |
| 01/02/2011 | Leyton Orient | 0 | 0 | Brighton | G Horwood |
| 05/02/2011 | Bristol Rvs | 2 | 4 | Brighton | P Miller |
| 12/02/2011 | Brighton | 4 | 1 | Hartlepool | G Ward |
| 22/02/2011 | Brighton | 4 | 0 | Plymouth | G Russell |
| 26/02/2011 | Milton Keynes Dons | 1 | 0 | Brighton | C Boyeson |
| 01/03/2011 | Yeovil | 0 | 1 | Brighton | S Mathieson |
| 05/03/2011 | Brighton | 4 | 3 | Carlisle | O Langford |
| 08/03/2011 | Brentford | 0 | 1 | Brighton | S Hooper |
| 12/03/2011 | Brighton | 2 | 0 | Tranmere | S Rushton |
| 19/03/2011 | Oldham | 0 | 1 | Brighton | D Whitestone |
| 22/03/2011 | Brighton | 1 | 0 | Notts County | P Crossley |
| 26/03/2011 | Brighton | 2 | 1 | Swindon | M Halsey |
| 29/03/2011 | Dag and Red | 0 | 1 | Brighton | A Woolmer |
| 02/04/2011 | Rochdale | 2 | 2 | Brighton | D Webb |
| 09/04/2011 | Brighton | 2 | 0 | Sheffield Weds | C Boyeson |
| 12/04/2011 | Brighton | 4 | 3 | Dag and Red | R East |
| 16/04/2011 | Walsall | 1 | 3 | Brighton | J Moss |
| 23/04/2011 | Brighton | 1 | 2 | Southampton | S Mathieson |
| 25/04/2011 | Colchester | 1 | 1 | Brighton | K Stroud |
| 30/04/2011 | Brighton | 2 | 3 | Huddersfield | S Tanner |
| 07/05/2011 | Notts County | 1 | 1 | Brighton | S Hooper |