Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 06/08/2017 | Bolton | 2 | 3 | Leeds | S Hooper |
| 12/08/2017 | Millwall | 1 | 1 | Bolton | A Davies |
| 15/08/2017 | Birmingham | 0 | 0 | Bolton | D England |
| 19/08/2017 | Bolton | 1 | 2 | Derby | S Martin |
| 25/08/2017 | Hull | 4 | 0 | Bolton | O Langford |
| 09/09/2017 | Bolton | 0 | 3 | Middlesbrough | G Eltringham |
| 12/09/2017 | Bolton | 0 | 1 | Sheffield United | S Attwell |
| 16/09/2017 | Ipswich | 2 | 0 | Bolton | A Madley |
| 23/09/2017 | Bolton | 0 | 3 | Brentford | D England |
| 26/09/2017 | Bristol City | 2 | 0 | Bolton | T Harrington |
| 30/09/2017 | Aston Villa | 1 | 0 | Bolton | J Simpson |
| 14/10/2017 | Bolton | 2 | 1 | Sheffield Weds | D Coote |
| 21/10/2017 | Bolton | 1 | 1 | QPR | J Linington |
| 28/10/2017 | Fulham | 1 | 1 | Bolton | G Eltringham |
| 31/10/2017 | Sunderland | 3 | 3 | Bolton | T Harrington |
| 04/11/2017 | Bolton | 2 | 1 | Norwich | S Martin |
| 17/11/2017 | Preston | 0 | 0 | Bolton | S Hooper |
| 21/11/2017 | Bolton | 2 | 2 | Reading | A Madley |
| 25/11/2017 | Wolves | 5 | 1 | Bolton | K Stroud |
| 02/12/2017 | Bolton | 3 | 1 | Barnsley | O Langford |
| 09/12/2017 | Nott'm Forest | 3 | 2 | Bolton | D England |
| 16/12/2017 | Bolton | 0 | 1 | Burton | A Madley |
| 23/12/2017 | Bolton | 2 | 0 | Cardiff | D Bond |
| 26/12/2017 | Middlesbrough | 2 | 0 | Bolton | J Simpson |
| 30/12/2017 | Sheffield United | 0 | 1 | Bolton | S Martin |
| 01/01/2018 | Bolton | 1 | 0 | Hull | G Eltringham |
| 13/01/2018 | Brentford | 2 | 0 | Bolton | A Davies |
| 20/01/2018 | Bolton | 1 | 1 | Ipswich | P Bankes |
| 02/02/2018 | Bolton | 1 | 0 | Bristol City | A Madley |
| 10/02/2018 | Bolton | 1 | 1 | Fulham | R Jones |
| 13/02/2018 | Cardiff | 2 | 0 | Bolton | T Robinson |
| 17/02/2018 | QPR | 2 | 0 | Bolton | S Duncan |
| 20/02/2018 | Bolton | 1 | 0 | Sunderland | D Coote |
| 24/02/2018 | Norwich | 0 | 0 | Bolton | K Stroud |
| 03/03/2018 | Bolton | 1 | 3 | Preston | P Bankes |
| 06/03/2018 | Reading | 1 | 1 | Bolton | J Linington |
| 10/03/2018 | Sheffield Weds | 1 | 1 | Bolton | D Bond |
| 17/03/2018 | Bolton | 1 | 0 | Aston Villa | R Jones |
| 30/03/2018 | Leeds | 2 | 1 | Bolton | G Eltringham |
| 03/04/2018 | Bolton | 0 | 1 | Birmingham | O Langford |
| 07/04/2018 | Derby | 3 | 0 | Bolton | D England |
| 10/04/2018 | Bolton | 0 | 2 | Millwall | R Jones |
| 14/04/2018 | Barnsley | 2 | 2 | Bolton | M Jones |
| 21/04/2018 | Bolton | 0 | 4 | Wolves | K Stroud |
| 28/04/2018 | Burton | 2 | 0 | Bolton | G Scott |
| 06/05/2018 | Bolton | 3 | 2 | Nott'm Forest | S Duncan |