Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 04/08/2018 | Coventry | 1 | 2 | Scunthorpe | A Coggins |
| 11/08/2018 | Scunthorpe | 1 | 1 | Walsall | D Whitestone |
| 19/08/2018 | Sunderland | 3 | 0 | Scunthorpe | A Backhouse |
| 22/08/2018 | Scunthorpe | 0 | 5 | Fleetwood Town | C Boyeson |
| 25/08/2018 | Scunthorpe | 2 | 2 | Barnsley | N Kinseley |
| 01/09/2018 | Accrington | 1 | 1 | Scunthorpe | C Sarginson |
| 08/09/2018 | Scunthorpe | 3 | 3 | Rochdale | R Joyce |
| 15/09/2018 | AFC Wimbledon | 2 | 3 | Scunthorpe | C Breakspear |
| 22/09/2018 | Scunthorpe | 1 | 0 | Shrewsbury | A Haines |
| 29/09/2018 | Burton | 0 | 0 | Scunthorpe | P Wright |
| 02/10/2018 | Scunthorpe | 5 | 3 | Charlton | D Drysdale |
| 06/10/2018 | Luton | 3 | 2 | Scunthorpe | K Johnson |
| 13/10/2018 | Scunthorpe | 0 | 2 | Peterboro | R Lewis |
| 20/10/2018 | Wycombe | 3 | 2 | Scunthorpe | A Young |
| 23/10/2018 | Blackpool | 1 | 0 | Scunthorpe | T Bramall |
| 27/10/2018 | Scunthorpe | 1 | 4 | Plymouth | S Oldham |
| 03/11/2018 | Scunthorpe | 3 | 3 | Oxford | P Marsden |
| 17/11/2018 | Bristol Rvs | 1 | 2 | Scunthorpe | L Collins |
| 24/11/2018 | Scunthorpe | 1 | 2 | Portsmouth | M Coy |
| 27/11/2018 | Southend | 2 | 0 | Scunthorpe | T Kettle |
| 08/12/2018 | Scunthorpe | 0 | 2 | Gillingham | G Salisbury |
| 15/12/2018 | Doncaster | 3 | 0 | Scunthorpe | A Woolmer |
| 22/12/2018 | Bradford | 2 | 0 | Scunthorpe | C Boyeson |
| 26/12/2018 | Scunthorpe | 0 | 2 | Luton | M Coy |
| 29/12/2018 | Scunthorpe | 1 | 0 | Wycombe | D Drysdale |
| 01/01/2019 | Peterboro | 0 | 2 | Scunthorpe | O Yates |
| 05/01/2019 | Scunthorpe | 2 | 1 | Coventry | E Ilderton |
| 12/01/2019 | Walsall | 1 | 2 | Scunthorpe | M Donohue |
| 19/01/2019 | Scunthorpe | 1 | 1 | Sunderland | C Hicks |
| 26/01/2019 | Fleetwood Town | 0 | 1 | Scunthorpe | S Stockbridge |
| 02/02/2019 | Barnsley | 2 | 0 | Scunthorpe | A Haines |
| 09/02/2019 | Scunthorpe | 2 | 0 | Accrington | A Coggins |
| 16/02/2019 | Gillingham | 1 | 0 | Scunthorpe | L Swabey |
| 23/02/2019 | Scunthorpe | 1 | 1 | Doncaster | J Brooks |
| 02/03/2019 | Oxford | 2 | 1 | Scunthorpe | M Salisbury |
| 09/03/2019 | Scunthorpe | 0 | 1 | Bristol Rvs | T Kettle |
| 12/03/2019 | Scunthorpe | 4 | 1 | Southend | B Toner |
| 16/03/2019 | Portsmouth | 2 | 0 | Scunthorpe | P Wright |
| 23/03/2019 | Rochdale | 3 | 1 | Scunthorpe | E Ilderton |
| 30/03/2019 | Scunthorpe | 1 | 2 | AFC Wimbledon | M Donohue |
| 06/04/2019 | Shrewsbury | 1 | 1 | Scunthorpe | P Marsden |
| 13/04/2019 | Scunthorpe | 0 | 3 | Burton | G Salisbury |
| 19/04/2019 | Scunthorpe | 0 | 0 | Blackpool | M Coy |
| 22/04/2019 | Charlton | 4 | 0 | Scunthorpe | B Huxtable |
| 27/04/2019 | Scunthorpe | 2 | 3 | Bradford | S Stockbridge |
| 04/05/2019 | Plymouth | 3 | 2 | Scunthorpe | R East |