Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 04/08/2018 | Grimsby | 1 | 4 | Forest Green | M Coy |
| 11/08/2018 | Macclesfield | 0 | 2 | Grimsby | O Langford |
| 18/08/2018 | Grimsby | 1 | 1 | Lincoln | C Boyeson |
| 21/08/2018 | Milton Keynes Dons | 1 | 1 | Grimsby | P Wright |
| 25/08/2018 | Newport County | 1 | 0 | Grimsby | N Hair |
| 01/09/2018 | Grimsby | 0 | 1 | Yeovil | T Bramall |
| 08/09/2018 | Bury | 4 | 0 | Grimsby | A Backhouse |
| 15/09/2018 | Grimsby | 0 | 3 | Oldham | N Kinseley |
| 22/09/2018 | Stevenage | 1 | 0 | Grimsby | L Collins |
| 29/09/2018 | Grimsby | 1 | 2 | Morecambe | C Sarginson |
| 02/10/2018 | Carlisle | 0 | 1 | Grimsby | M Coy |
| 06/10/2018 | Grimsby | 2 | 0 | Port Vale | A Haines |
| 20/10/2018 | Grimsby | 0 | 0 | Exeter | M Donohue |
| 23/10/2018 | Grimsby | 1 | 0 | Colchester | G Salisbury |
| 27/10/2018 | Crewe | 2 | 0 | Grimsby | P Wright |
| 03/11/2018 | Cambridge | 1 | 0 | Grimsby | N Kinseley |
| 06/11/2018 | Mansfield | 2 | 1 | Grimsby | K Stroud |
| 17/11/2018 | Grimsby | 1 | 0 | Crawley Town | A Haines |
| 24/11/2018 | Northampton | 2 | 2 | Grimsby | T Kettle |
| 27/11/2018 | Grimsby | 5 | 2 | Tranmere | D Drysdale |
| 08/12/2018 | Cheltenham | 2 | 1 | Grimsby | P Marsden |
| 15/12/2018 | Grimsby | 2 | 1 | Swindon | S Oldham |
| 22/12/2018 | Grimsby | 4 | 0 | Notts County | D Webb |
| 26/12/2018 | Port Vale | 0 | 1 | Grimsby | B Toner |
| 29/12/2018 | Exeter | 1 | 2 | Grimsby | C Sarginson |
| 01/01/2019 | Grimsby | 0 | 1 | Mansfield | M Donohue |
| 12/01/2019 | Grimsby | 0 | 2 | Macclesfield | S Stockbridge |
| 19/01/2019 | Lincoln | 1 | 0 | Grimsby | M Dean |
| 22/01/2019 | Forest Green | 3 | 0 | Grimsby | A Coggins |
| 26/01/2019 | Grimsby | 1 | 0 | Milton Keynes Dons | P Marsden |
| 02/02/2019 | Grimsby | 3 | 0 | Newport County | A Backhouse |
| 09/02/2019 | Yeovil | 1 | 3 | Grimsby | C Breakspear |
| 16/02/2019 | Grimsby | 1 | 0 | Cheltenham | T Kettle |
| 23/02/2019 | Swindon | 1 | 1 | Grimsby | N Hair |
| 02/03/2019 | Grimsby | 0 | 2 | Cambridge | S Oldham |
| 09/03/2019 | Crawley Town | 2 | 1 | Grimsby | B Huxtable |
| 12/03/2019 | Tranmere | 4 | 1 | Grimsby | G Salisbury |
| 16/03/2019 | Grimsby | 0 | 0 | Northampton | O Yates |
| 23/03/2019 | Grimsby | 0 | 0 | Bury | A Backhouse |
| 30/03/2019 | Oldham | 2 | 0 | Grimsby | J Adcock |
| 06/04/2019 | Grimsby | 0 | 2 | Stevenage | T Kettle |
| 13/04/2019 | Morecambe | 1 | 1 | Grimsby | S Oldham |
| 19/04/2019 | Colchester | 1 | 0 | Grimsby | C Sarginson |
| 22/04/2019 | Grimsby | 1 | 0 | Carlisle | P Marsden |
| 27/04/2019 | Notts County | 2 | 1 | Grimsby | A Haines |
| 04/05/2019 | Grimsby | 2 | 0 | Crewe | C Hicks |