Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 04/08/2018 | Exeter | 3 | 1 | Carlisle | G Salisbury |
| 11/08/2018 | Carlisle | 2 | 2 | Northampton | T Nield |
| 18/08/2018 | Cheltenham | 0 | 1 | Carlisle | P Wright |
| 21/08/2018 | Carlisle | 2 | 1 | Port Vale | B Toner |
| 25/08/2018 | Carlisle | 1 | 0 | Crewe | S Stockbridge |
| 01/09/2018 | Mansfield | 1 | 0 | Carlisle | D Drysdale |
| 08/09/2018 | Cambridge | 1 | 2 | Carlisle | O Yates |
| 15/09/2018 | Carlisle | 0 | 2 | Tranmere | M Donohue |
| 22/09/2018 | Bury | 0 | 1 | Carlisle | M Heywood |
| 29/09/2018 | Carlisle | 0 | 1 | Stevenage | S Oldham |
| 02/10/2018 | Carlisle | 0 | 1 | Grimsby | M Coy |
| 06/10/2018 | Oldham | 1 | 3 | Carlisle | D Whitestone |
| 13/10/2018 | Carlisle | 0 | 2 | Morecambe | S Stockbridge |
| 20/10/2018 | Macclesfield | 2 | 1 | Carlisle | M Salisbury |
| 23/10/2018 | Lincoln | 2 | 2 | Carlisle | N Hair |
| 27/10/2018 | Carlisle | 0 | 1 | Yeovil | T Bramall |
| 03/11/2018 | Carlisle | 3 | 2 | Newport County | C Sarginson |
| 17/11/2018 | Swindon | 0 | 4 | Carlisle | G Salisbury |
| 24/11/2018 | Carlisle | 1 | 2 | Forest Green | C Boyeson |
| 27/11/2018 | Notts County | 1 | 1 | Carlisle | T Bramall |
| 08/12/2018 | Milton Keynes Dons | 2 | 0 | Carlisle | S Oldham |
| 15/12/2018 | Carlisle | 4 | 0 | Colchester | E Ilderton |
| 22/12/2018 | Crawley Town | 2 | 3 | Carlisle | N Kinseley |
| 26/12/2018 | Carlisle | 6 | 0 | Oldham | A Haines |
| 29/12/2018 | Carlisle | 2 | 1 | Macclesfield | R Joyce |
| 01/01/2019 | Morecambe | 0 | 2 | Carlisle | B Toner |
| 05/01/2019 | Carlisle | 3 | 2 | Mansfield | R Lewis |
| 12/01/2019 | Northampton | 3 | 0 | Carlisle | L Swabey |
| 19/01/2019 | Carlisle | 2 | 0 | Cheltenham | C Boyeson |
| 26/01/2019 | Port Vale | 0 | 1 | Carlisle | C Breakspear |
| 09/02/2019 | Carlisle | 1 | 1 | Exeter | M Donohue |
| 12/02/2019 | Crewe | 2 | 1 | Carlisle | P Marsden |
| 16/02/2019 | Carlisle | 2 | 3 | Milton Keynes Dons | P Wright |
| 23/02/2019 | Colchester | 1 | 1 | Carlisle | T Kettle |
| 02/03/2019 | Newport County | 2 | 0 | Carlisle | R Joyce |
| 09/03/2019 | Carlisle | 2 | 1 | Swindon | B Toner |
| 12/03/2019 | Carlisle | 1 | 3 | Notts County | E Ilderton |
| 16/03/2019 | Forest Green | 1 | 1 | Carlisle | G Salisbury |
| 23/03/2019 | Carlisle | 2 | 2 | Cambridge | A Haines |
| 30/03/2019 | Tranmere | 3 | 0 | Carlisle | S Duncan |
| 06/04/2019 | Carlisle | 3 | 2 | Bury | C Sarginson |
| 13/04/2019 | Stevenage | 3 | 0 | Carlisle | C Boyeson |
| 19/04/2019 | Carlisle | 1 | 0 | Lincoln | L Mason |
| 22/04/2019 | Grimsby | 1 | 0 | Carlisle | P Marsden |
| 27/04/2019 | Carlisle | 4 | 2 | Crawley Town | S Oldham |
| 04/05/2019 | Yeovil | 0 | 0 | Carlisle | M Donohue |