Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 05/08/2017 | Milton Keynes Dons | 0 | 1 | Wigan | K Johnson |
| 13/08/2017 | Wigan | 4 | 1 | Bury | O Langford |
| 19/08/2017 | Oldham | 0 | 2 | Wigan | E Ilderton |
| 26/08/2017 | Wigan | 1 | 1 | Portsmouth | R Jones |
| 09/09/2017 | Shrewsbury | 1 | 0 | Wigan | M Heywood |
| 12/09/2017 | Charlton | 0 | 3 | Wigan | C Breakspear |
| 16/09/2017 | Wigan | 3 | 0 | Bristol Rvs | C Boyeson |
| 19/09/2017 | Wigan | 1 | 0 | Northampton | A Backhouse |
| 23/09/2017 | Peterboro | 3 | 2 | Wigan | C Sarginson |
| 26/09/2017 | Wigan | 1 | 0 | Plymouth | S Stockbridge |
| 30/09/2017 | Wigan | 2 | 0 | Walsall | D Coote |
| 07/10/2017 | Scunthorpe | 1 | 2 | Wigan | R Lewis |
| 14/10/2017 | Wigan | 3 | 0 | Southend | J Busby |
| 17/10/2017 | Gillingham | 1 | 1 | Wigan | B Huxtable |
| 21/10/2017 | Blackpool | 1 | 3 | Wigan | A Haines |
| 28/10/2017 | Wigan | 0 | 0 | Blackburn | D England |
| 18/11/2017 | Wigan | 1 | 2 | Bradford | D Webb |
| 21/11/2017 | Wigan | 3 | 0 | Doncaster | C Boyeson |
| 25/11/2017 | Rotherham | 1 | 3 | Wigan | S Stockbridge |
| 09/12/2017 | Wigan | 2 | 0 | Fleetwood Town | A Haines |
| 16/12/2017 | AFC Wimbledon | 0 | 4 | Wigan | B Huxtable |
| 23/12/2017 | Oxford | 0 | 7 | Wigan | R Lewis |
| 26/12/2017 | Wigan | 0 | 0 | Shrewsbury | D Webb |
| 29/12/2017 | Wigan | 0 | 0 | Charlton | T Kettle |
| 01/01/2018 | Northampton | 0 | 1 | Wigan | M Heywood |
| 13/01/2018 | Wigan | 0 | 0 | Peterboro | E Ilderton |
| 20/01/2018 | Plymouth | 1 | 3 | Wigan | G Ward |
| 03/02/2018 | Wigan | 2 | 0 | Gillingham | N Kinseley |
| 10/02/2018 | Southend | 3 | 1 | Wigan | A Woolmer |
| 13/02/2018 | Wigan | 0 | 2 | Blackpool | J Simpson |
| 24/02/2018 | Wigan | 1 | 0 | Rochdale | B Toner |
| 04/03/2018 | Blackburn | 2 | 2 | Wigan | G Eltringham |
| 10/03/2018 | Wigan | 3 | 3 | Scunthorpe | D Whitestone |
| 14/03/2018 | Bradford | 0 | 1 | Wigan | M Coy |
| 21/03/2018 | Walsall | 0 | 3 | Wigan | J Brooks |
| 24/03/2018 | Bury | 0 | 2 | Wigan | J Moss |
| 30/03/2018 | Wigan | 3 | 0 | Oldham | R Jones |
| 02/04/2018 | Portsmouth | 2 | 1 | Wigan | T Robinson |
| 07/04/2018 | Wigan | 5 | 1 | Milton Keynes Dons | S Stockbridge |
| 10/04/2018 | Rochdale | 1 | 4 | Wigan | D Webb |
| 14/04/2018 | Wigan | 0 | 0 | Rotherham | C Sarginson |
| 17/04/2018 | Wigan | 1 | 0 | Oxford | T Kettle |
| 21/04/2018 | Fleetwood Town | 0 | 4 | Wigan | D Whitestone |
| 24/04/2018 | Bristol Rvs | 1 | 1 | Wigan | S Martin |
| 28/04/2018 | Wigan | 1 | 1 | AFC Wimbledon | A Woolmer |
| 05/05/2018 | Doncaster | 0 | 1 | Wigan | D Webb |