Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 05/08/2017 | Scunthorpe | 1 | 1 | AFC Wimbledon | M Salisbury |
| 12/08/2017 | Rochdale | 1 | 1 | Scunthorpe | R Joyce |
| 19/08/2017 | Scunthorpe | 1 | 0 | Oxford | D Handley |
| 26/08/2017 | Plymouth | 0 | 4 | Scunthorpe | C Sarginson |
| 02/09/2017 | Bury | 0 | 1 | Scunthorpe | E Ilderton |
| 09/09/2017 | Scunthorpe | 0 | 0 | Blackpool | A Haines |
| 12/09/2017 | Scunthorpe | 0 | 1 | Blackburn | S Stockbridge |
| 17/09/2017 | Doncaster | 0 | 1 | Scunthorpe | D Webb |
| 23/09/2017 | Scunthorpe | 2 | 0 | Portsmouth | A Backhouse |
| 26/09/2017 | Gillingham | 0 | 0 | Scunthorpe | A Coggins |
| 30/09/2017 | Shrewsbury | 2 | 0 | Scunthorpe | G Horwood |
| 07/10/2017 | Scunthorpe | 1 | 2 | Wigan | R Lewis |
| 14/10/2017 | Rotherham | 2 | 0 | Scunthorpe | D Bond |
| 17/10/2017 | Scunthorpe | 1 | 1 | Fleetwood Town | P Bankes |
| 21/10/2017 | Scunthorpe | 2 | 1 | Peterboro | M Heywood |
| 28/10/2017 | Oldham | 2 | 3 | Scunthorpe | S Oldham |
| 11/11/2017 | Scunthorpe | 1 | 0 | Bristol Rvs | S Stockbridge |
| 18/11/2017 | Northampton | 0 | 3 | Scunthorpe | M Salisbury |
| 21/11/2017 | Bradford | 1 | 2 | Scunthorpe | S Duncan |
| 25/11/2017 | Scunthorpe | 2 | 0 | Charlton | K Johnson |
| 09/12/2017 | Walsall | 1 | 0 | Scunthorpe | S Oldham |
| 16/12/2017 | Scunthorpe | 2 | 2 | Milton Keynes Dons | G Salisbury |
| 23/12/2017 | Scunthorpe | 3 | 1 | Southend | M Coy |
| 26/12/2017 | Blackpool | 2 | 3 | Scunthorpe | R Joyce |
| 30/12/2017 | Blackburn | 2 | 2 | Scunthorpe | A Haines |
| 01/01/2018 | Scunthorpe | 1 | 0 | Bury | B Toner |
| 13/01/2018 | Portsmouth | 1 | 1 | Scunthorpe | C Breakspear |
| 20/01/2018 | Scunthorpe | 1 | 3 | Gillingham | C Boyeson |
| 23/01/2018 | Scunthorpe | 1 | 1 | Doncaster | E Ilderton |
| 27/01/2018 | Southend | 3 | 2 | Scunthorpe | C Hicks |
| 03/02/2018 | Fleetwood Town | 2 | 3 | Scunthorpe | M Heywood |
| 10/02/2018 | Scunthorpe | 1 | 2 | Rotherham | G Salisbury |
| 13/02/2018 | Peterboro | 2 | 2 | Scunthorpe | T Kettle |
| 17/02/2018 | Scunthorpe | 2 | 2 | Northampton | A Madley |
| 24/02/2018 | Bristol Rvs | 1 | 1 | Scunthorpe | D Handley |
| 03/03/2018 | Scunthorpe | 0 | 2 | Oldham | J Busby |
| 10/03/2018 | Wigan | 3 | 3 | Scunthorpe | D Whitestone |
| 17/03/2018 | Scunthorpe | 1 | 2 | Shrewsbury | M Salisbury |
| 24/03/2018 | Scunthorpe | 1 | 1 | Rochdale | J Brooks |
| 30/03/2018 | Oxford | 1 | 1 | Scunthorpe | D Drysdale |
| 07/04/2018 | AFC Wimbledon | 1 | 1 | Scunthorpe | T Nield |
| 14/04/2018 | Charlton | 0 | 1 | Scunthorpe | G Salisbury |
| 21/04/2018 | Scunthorpe | 1 | 0 | Walsall | D Webb |
| 28/04/2018 | Milton Keynes Dons | 0 | 2 | Scunthorpe | J Busby |
| 01/05/2018 | Scunthorpe | 2 | 0 | Plymouth | B Toner |
| 05/05/2018 | Scunthorpe | 1 | 1 | Bradford | J Brooks |