Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 05/08/2017 | Wolves | 1 | 0 | Middlesbrough | D Bond |
| 12/08/2017 | Middlesbrough | 1 | 0 | Sheffield United | P Bankes |
| 15/08/2017 | Middlesbrough | 2 | 0 | Burton | T Robinson |
| 19/08/2017 | Nott'm Forest | 2 | 1 | Middlesbrough | G Scott |
| 26/08/2017 | Middlesbrough | 0 | 0 | Preston | D England |
| 09/09/2017 | Bolton | 0 | 3 | Middlesbrough | G Eltringham |
| 12/09/2017 | Aston Villa | 0 | 0 | Middlesbrough | J Linington |
| 16/09/2017 | Middlesbrough | 3 | 2 | QPR | D Bond |
| 23/09/2017 | Fulham | 1 | 1 | Middlesbrough | O Langford |
| 26/09/2017 | Middlesbrough | 0 | 1 | Norwich | J Simpson |
| 30/09/2017 | Middlesbrough | 2 | 2 | Brentford | P Tierney |
| 14/10/2017 | Barnsley | 2 | 2 | Middlesbrough | L Mason |
| 21/10/2017 | Middlesbrough | 0 | 1 | Cardiff | A Madley |
| 28/10/2017 | Reading | 0 | 2 | Middlesbrough | O Langford |
| 31/10/2017 | Hull | 1 | 3 | Middlesbrough | T Robinson |
| 05/11/2017 | Middlesbrough | 1 | 0 | Sunderland | J Simpson |
| 19/11/2017 | Leeds | 2 | 1 | Middlesbrough | K Stroud |
| 22/11/2017 | Middlesbrough | 2 | 0 | Birmingham | D England |
| 25/11/2017 | Middlesbrough | 0 | 3 | Derby | S Hooper |
| 02/12/2017 | Bristol City | 2 | 1 | Middlesbrough | S Martin |
| 09/12/2017 | Middlesbrough | 2 | 0 | Ipswich | R Jones |
| 16/12/2017 | Millwall | 2 | 1 | Middlesbrough | O Langford |
| 23/12/2017 | Sheffield Weds | 1 | 2 | Middlesbrough | P Bankes |
| 26/12/2017 | Middlesbrough | 2 | 0 | Bolton | J Simpson |
| 30/12/2017 | Middlesbrough | 0 | 1 | Aston Villa | A Madley |
| 01/01/2018 | Preston | 2 | 3 | Middlesbrough | D Coote |
| 13/01/2018 | Middlesbrough | 0 | 1 | Fulham | G Eltringham |
| 20/01/2018 | QPR | 0 | 3 | Middlesbrough | O Langford |
| 30/01/2018 | Middlesbrough | 0 | 0 | Sheffield Weds | J Linington |
| 03/02/2018 | Norwich | 1 | 0 | Middlesbrough | M Jones |
| 10/02/2018 | Middlesbrough | 2 | 1 | Reading | D Coote |
| 17/02/2018 | Cardiff | 1 | 0 | Middlesbrough | D Bond |
| 20/02/2018 | Middlesbrough | 3 | 1 | Hull | A Madley |
| 24/02/2018 | Sunderland | 3 | 3 | Middlesbrough | T Robinson |
| 02/03/2018 | Middlesbrough | 3 | 0 | Leeds | D England |
| 06/03/2018 | Birmingham | 0 | 1 | Middlesbrough | S Martin |
| 10/03/2018 | Middlesbrough | 3 | 1 | Barnsley | A Davies |
| 17/03/2018 | Brentford | 1 | 1 | Middlesbrough | S Hooper |
| 30/03/2018 | Middlesbrough | 1 | 2 | Wolves | S Attwell |
| 02/04/2018 | Burton | 1 | 1 | Middlesbrough | D Coote |
| 07/04/2018 | Middlesbrough | 2 | 0 | Nott'm Forest | D Webb |
| 10/04/2018 | Sheffield United | 2 | 1 | Middlesbrough | D Bond |
| 14/04/2018 | Middlesbrough | 2 | 1 | Bristol City | A Madley |
| 21/04/2018 | Derby | 1 | 2 | Middlesbrough | L Probert |
| 28/04/2018 | Middlesbrough | 2 | 0 | Millwall | P Tierney |
| 06/05/2018 | Ipswich | 2 | 2 | Middlesbrough | D Coote |