Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 05/08/2017 | Scunthorpe | 1 | 1 | AFC Wimbledon | M Salisbury |
| 12/08/2017 | AFC Wimbledon | 0 | 1 | Shrewsbury | C Breakspear |
| 19/08/2017 | Fleetwood Town | 2 | 0 | AFC Wimbledon | J Brooks |
| 26/08/2017 | AFC Wimbledon | 2 | 0 | Doncaster | G Ward |
| 02/09/2017 | Blackpool | 1 | 0 | AFC Wimbledon | C Boyeson |
| 09/09/2017 | AFC Wimbledon | 0 | 2 | Portsmouth | K Johnson |
| 12/09/2017 | AFC Wimbledon | 1 | 1 | Gillingham | N Kinseley |
| 16/09/2017 | Blackburn | 0 | 1 | AFC Wimbledon | T Kettle |
| 22/09/2017 | AFC Wimbledon | 0 | 2 | Milton Keynes Dons | M Jones |
| 26/09/2017 | Southend | 1 | 0 | AFC Wimbledon | G Horwood |
| 30/09/2017 | AFC Wimbledon | 0 | 0 | Rochdale | C Sarginson |
| 07/10/2017 | Oxford | 3 | 0 | AFC Wimbledon | D Drysdale |
| 14/10/2017 | Northampton | 0 | 1 | AFC Wimbledon | G Salisbury |
| 17/10/2017 | AFC Wimbledon | 3 | 1 | Rotherham | D Whitestone |
| 21/10/2017 | AFC Wimbledon | 0 | 1 | Plymouth | M Coy |
| 28/10/2017 | Charlton | 1 | 0 | AFC Wimbledon | B Toner |
| 12/11/2017 | AFC Wimbledon | 2 | 2 | Peterboro | D Handley |
| 18/11/2017 | Bristol Rvs | 1 | 3 | AFC Wimbledon | J Brooks |
| 21/11/2017 | Oldham | 0 | 0 | AFC Wimbledon | R Lewis |
| 25/11/2017 | AFC Wimbledon | 1 | 2 | Walsall | J Busby |
| 16/12/2017 | AFC Wimbledon | 0 | 4 | Wigan | B Huxtable |
| 23/12/2017 | AFC Wimbledon | 2 | 1 | Bradford | G Horwood |
| 26/12/2017 | Portsmouth | 2 | 1 | AFC Wimbledon | L Collins |
| 30/12/2017 | Gillingham | 2 | 2 | AFC Wimbledon | R Lewis |
| 01/01/2018 | AFC Wimbledon | 2 | 0 | Southend | J Busby |
| 13/01/2018 | Milton Keynes Dons | 0 | 0 | AFC Wimbledon | P Tierney |
| 20/01/2018 | AFC Wimbledon | 2 | 0 | Blackpool | D Drysdale |
| 27/01/2018 | Bradford | 0 | 4 | AFC Wimbledon | G Eltringham |
| 03/02/2018 | Rotherham | 2 | 0 | AFC Wimbledon | M Salisbury |
| 06/02/2018 | Bury | 2 | 1 | AFC Wimbledon | R Jones |
| 10/02/2018 | AFC Wimbledon | 1 | 3 | Northampton | C Boyeson |
| 13/02/2018 | Plymouth | 4 | 2 | AFC Wimbledon | B Huxtable |
| 17/02/2018 | AFC Wimbledon | 1 | 0 | Bristol Rvs | C Breakspear |
| 24/02/2018 | Peterboro | 1 | 1 | AFC Wimbledon | A Backhouse |
| 27/02/2018 | AFC Wimbledon | 0 | 3 | Blackburn | G Scott |
| 10/03/2018 | AFC Wimbledon | 2 | 1 | Oxford | C Sarginson |
| 17/03/2018 | Rochdale | 1 | 1 | AFC Wimbledon | S Oldham |
| 24/03/2018 | Shrewsbury | 1 | 0 | AFC Wimbledon | D Drysdale |
| 30/03/2018 | AFC Wimbledon | 0 | 1 | Fleetwood Town | C Breakspear |
| 07/04/2018 | AFC Wimbledon | 1 | 1 | Scunthorpe | T Nield |
| 10/04/2018 | AFC Wimbledon | 1 | 0 | Charlton | C Hicks |
| 14/04/2018 | Walsall | 2 | 3 | AFC Wimbledon | M Heywood |
| 21/04/2018 | AFC Wimbledon | 2 | 2 | Oldham | A Davies |
| 28/04/2018 | Wigan | 1 | 1 | AFC Wimbledon | A Woolmer |
| 01/05/2018 | Doncaster | 0 | 0 | AFC Wimbledon | J Brooks |
| 05/05/2018 | AFC Wimbledon | 2 | 2 | Bury | D Drysdale |