Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 06/08/2016 | Reading | 1 | 0 | Preston | A Davies |
| 13/08/2016 | Preston | 1 | 2 | Fulham | J Adcock |
| 16/08/2016 | Preston | 0 | 1 | Derby | D Coote |
| 20/08/2016 | QPR | 0 | 2 | Preston | A Madley |
| 27/08/2016 | Ipswich | 1 | 0 | Preston | T Robinson |
| 10/09/2016 | Preston | 1 | 2 | Barnsley | G Eltringham |
| 13/09/2016 | Preston | 3 | 0 | Cardiff | S Martin |
| 17/09/2016 | Brentford | 5 | 0 | Preston | K Stroud |
| 23/09/2016 | Preston | 1 | 0 | Wigan | O Langford |
| 27/09/2016 | Birmingham | 2 | 2 | Preston | A Woolmer |
| 01/10/2016 | Preston | 2 | 0 | Aston Villa | P Bankes |
| 15/10/2016 | Brighton | 2 | 2 | Preston | C Pawson |
| 19/10/2016 | Preston | 3 | 1 | Huddersfield | J Simpson |
| 22/10/2016 | Norwich | 0 | 1 | Preston | S Martin |
| 29/10/2016 | Preston | 1 | 2 | Newcastle | C Kavanagh |
| 05/11/2016 | Rotherham | 1 | 3 | Preston | A Woolmer |
| 19/11/2016 | Preston | 0 | 0 | Wolves | J Linington |
| 26/11/2016 | Preston | 1 | 1 | Burton | D Bond |
| 03/12/2016 | Sheffield Weds | 2 | 1 | Preston | S Duncan |
| 10/12/2016 | Preston | 3 | 2 | Blackburn | K Friend |
| 14/12/2016 | Nott'm Forest | 1 | 1 | Preston | T Harrington |
| 17/12/2016 | Bristol City | 1 | 2 | Preston | S Hooper |
| 26/12/2016 | Preston | 1 | 4 | Leeds | J Simpson |
| 31/12/2016 | Preston | 1 | 1 | Sheffield Weds | A Woolmer |
| 02/01/2017 | Burton | 0 | 1 | Preston | O Langford |
| 14/01/2017 | Preston | 2 | 0 | Brighton | S Hooper |
| 21/01/2017 | Aston Villa | 2 | 2 | Preston | A Madley |
| 28/01/2017 | Preston | 1 | 1 | Ipswich | S Martin |
| 31/01/2017 | Cardiff | 2 | 0 | Preston | G Scott |
| 04/02/2017 | Barnsley | 0 | 0 | Preston | O Langford |
| 11/02/2017 | Preston | 4 | 2 | Brentford | T Harrington |
| 14/02/2017 | Preston | 2 | 1 | Birmingham | T Robinson |
| 18/02/2017 | Wigan | 0 | 0 | Preston | C Kavanagh |
| 25/02/2017 | Preston | 2 | 1 | QPR | D Coote |
| 04/03/2017 | Fulham | 3 | 1 | Preston | S Hooper |
| 07/03/2017 | Derby | 1 | 1 | Preston | J Linington |
| 11/03/2017 | Preston | 3 | 0 | Reading | S Duncan |
| 18/03/2017 | Blackburn | 2 | 2 | Preston | S Attwell |
| 01/04/2017 | Preston | 1 | 1 | Nott'm Forest | D Bond |
| 04/04/2017 | Preston | 5 | 0 | Bristol City | A Madley |
| 08/04/2017 | Leeds | 3 | 0 | Preston | P Bankes |
| 14/04/2017 | Huddersfield | 3 | 2 | Preston | L Probert |
| 17/04/2017 | Preston | 1 | 3 | Norwich | J Adcock |
| 24/04/2017 | Newcastle | 4 | 1 | Preston | A Madley |
| 29/04/2017 | Preston | 1 | 1 | Rotherham | R Jones |
| 07/05/2017 | Wolves | 1 | 0 | Preston | D England |