Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 06/08/2011 | Middlesbrough | 2 | 2 | Portsmouth | G Salisbury |
| 13/08/2011 | Portsmouth | 0 | 1 | Brighton | N Swarbrick |
| 16/08/2011 | Portsmouth | 1 | 0 | Reading | A D'Urso |
| 20/08/2011 | Bristol City | 0 | 0 | Portsmouth | M Naylor |
| 27/08/2011 | Portsmouth | 1 | 1 | Cardiff | A Woolmer |
| 10/09/2011 | West Ham | 4 | 3 | Portsmouth | R East |
| 17/09/2011 | Hull | 1 | 0 | Portsmouth | A Haines |
| 24/09/2011 | Portsmouth | 1 | 0 | Blackpool | D Deadman |
| 27/09/2011 | Portsmouth | 2 | 3 | Peterboro | P Miller |
| 01/10/2011 | Leeds | 1 | 0 | Portsmouth | N Miller |
| 15/10/2011 | Portsmouth | 2 | 0 | Barnsley | S Hooper |
| 18/10/2011 | Ipswich | 1 | 0 | Portsmouth | G Ward |
| 22/10/2011 | Portsmouth | 3 | 1 | Doncaster | F Graham |
| 29/10/2011 | Derby | 3 | 1 | Portsmouth | C Pawson |
| 01/11/2011 | Crystal Palace | 0 | 0 | Portsmouth | D Drysdale |
| 05/11/2011 | Portsmouth | 3 | 0 | Nott'm Forest | A Bates |
| 19/11/2011 | Watford | 2 | 0 | Portsmouth | G Scott |
| 26/11/2011 | Portsmouth | 1 | 1 | Leicester | P Gibbs |
| 03/12/2011 | Portsmouth | 2 | 1 | Coventry | C Boyeson |
| 10/12/2011 | Burnley | 0 | 1 | Portsmouth | S Rushton |
| 18/12/2011 | Portsmouth | 1 | 1 | Southampton | M Halsey |
| 26/12/2011 | Millwall | 1 | 0 | Portsmouth | N Miller |
| 31/12/2011 | Leicester | 1 | 1 | Portsmouth | C Webster |
| 02/01/2012 | Portsmouth | 2 | 0 | Watford | I Williamson |
| 14/01/2012 | Portsmouth | 0 | 1 | West Ham | K Friend |
| 21/01/2012 | Cardiff | 3 | 2 | Portsmouth | S Tanner |
| 28/01/2012 | Peterboro | 0 | 3 | Portsmouth | D Webb |
| 07/02/2012 | Birmingham | 1 | 0 | Portsmouth | D Drysdale |
| 11/02/2012 | Blackpool | 1 | 1 | Portsmouth | R Madley |
| 14/02/2012 | Portsmouth | 0 | 1 | Ipswich | D Deadman |
| 18/02/2012 | Barnsley | 2 | 0 | Portsmouth | E Ilderton |
| 25/02/2012 | Portsmouth | 0 | 0 | Leeds | P Gibbs |
| 03/03/2012 | Portsmouth | 1 | 3 | Middlesbrough | T Kettle |
| 06/03/2012 | Reading | 1 | 0 | Portsmouth | O Langford |
| 10/03/2012 | Brighton | 2 | 0 | Portsmouth | M Dean |
| 17/03/2012 | Portsmouth | 0 | 0 | Bristol City | A D'Urso |
| 20/03/2012 | Portsmouth | 4 | 1 | Birmingham | B Malone |
| 24/03/2012 | Coventry | 2 | 0 | Portsmouth | G Eltringham |
| 27/03/2012 | Portsmouth | 2 | 0 | Hull | D Sheldrake |
| 31/03/2012 | Portsmouth | 1 | 5 | Burnley | S Attwell |
| 07/04/2012 | Southampton | 2 | 2 | Portsmouth | N Swarbrick |
| 10/04/2012 | Portsmouth | 0 | 1 | Millwall | M Halsey |
| 14/04/2012 | Doncaster | 3 | 4 | Portsmouth | M Russell |
| 17/04/2012 | Portsmouth | 2 | 1 | Crystal Palace | S Hooper |
| 21/04/2012 | Portsmouth | 1 | 2 | Derby | M Naylor |
| 28/04/2012 | Nott'm Forest | 2 | 0 | Portsmouth | M Haywood |