Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 06/08/2011 | Tranmere | 1 | 0 | Chesterfield | O Langford |
| 13/08/2011 | Chesterfield | 1 | 1 | Stevenage | G Eltringham |
| 16/08/2011 | Chesterfield | 0 | 2 | Preston | A Bates |
| 20/08/2011 | Milton Keynes Dons | 6 | 2 | Chesterfield | G Ward |
| 27/08/2011 | Exeter | 2 | 1 | Chesterfield | C Sarginson |
| 03/09/2011 | Chesterfield | 0 | 0 | Leyton Orient | G Sutton |
| 10/09/2011 | Bournemouth | 0 | 3 | Chesterfield | D Deadman |
| 13/09/2011 | Chesterfield | 1 | 0 | Bury | C Pawson |
| 17/09/2011 | Chesterfield | 4 | 1 | Carlisle | N Miller |
| 24/09/2011 | Charlton | 3 | 1 | Chesterfield | G Scott |
| 01/10/2011 | Chesterfield | 0 | 1 | Colchester | D Mohareb |
| 08/10/2011 | Sheffield Weds | 3 | 1 | Chesterfield | K Wright |
| 15/10/2011 | Chesterfield | 1 | 3 | Notts County | E Ilderton |
| 22/10/2011 | Chesterfield | 2 | 3 | Hartlepool | R Madley |
| 25/10/2011 | Rochdale | 1 | 1 | Chesterfield | D Drysdale |
| 29/10/2011 | Brentford | 2 | 1 | Chesterfield | I Williamson |
| 05/11/2011 | Chesterfield | 2 | 2 | Yeovil | A Madley |
| 19/11/2011 | Oldham | 5 | 2 | Chesterfield | R Lewis |
| 26/11/2011 | Chesterfield | 0 | 1 | Sheffield United | D Sheldrake |
| 10/12/2011 | Wycombe | 3 | 2 | Chesterfield | L Collins |
| 17/12/2011 | Chesterfield | 1 | 1 | Walsall | G Sutton |
| 26/12/2011 | Huddersfield | 1 | 0 | Chesterfield | C Boyeson |
| 31/12/2011 | Scunthorpe | 2 | 2 | Chesterfield | A Haines |
| 02/01/2012 | Chesterfield | 1 | 1 | Oldham | D Deadman |
| 07/01/2012 | Chesterfield | 0 | 2 | Exeter | D Coote |
| 14/01/2012 | Leyton Orient | 1 | 1 | Chesterfield | G Scott |
| 21/01/2012 | Colchester | 1 | 2 | Chesterfield | M Brown |
| 27/01/2012 | Chesterfield | 1 | 0 | Bournemouth | A Marriner |
| 04/02/2012 | Carlisle | 2 | 1 | Chesterfield | G Eltringham |
| 14/02/2012 | Bury | 1 | 1 | Chesterfield | E Ilderton |
| 18/02/2012 | Chesterfield | 1 | 0 | Sheffield Weds | N Miller |
| 25/02/2012 | Notts County | 1 | 0 | Chesterfield | P Tierney |
| 28/02/2012 | Chesterfield | 0 | 4 | Charlton | C Webster |
| 03/03/2012 | Chesterfield | 1 | 0 | Tranmere | D Whitestone |
| 06/03/2012 | Preston | 0 | 0 | Chesterfield | M Heywood |
| 10/03/2012 | Stevenage | 2 | 2 | Chesterfield | L Collins |
| 17/03/2012 | Chesterfield | 1 | 1 | Milton Keynes Dons | S Rushton |
| 20/03/2012 | Chesterfield | 0 | 2 | Huddersfield | C Sarginson |
| 28/03/2012 | Sheffield United | 4 | 1 | Chesterfield | S Hooper |
| 31/03/2012 | Chesterfield | 1 | 4 | Scunthorpe | A Haines |
| 07/04/2012 | Walsall | 3 | 2 | Chesterfield | M Russell |
| 09/04/2012 | Chesterfield | 4 | 0 | Wycombe | T Kettle |
| 14/04/2012 | Hartlepool | 1 | 2 | Chesterfield | M Haywood |
| 21/04/2012 | Chesterfield | 2 | 1 | Rochdale | C Pawson |
| 28/04/2012 | Yeovil | 3 | 2 | Chesterfield | D Mohareb |
| 05/05/2012 | Chesterfield | 2 | 3 | Brentford | D McDermid |