Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 07/08/2010 | Southend | 1 | 1 | Stockport | I Williamson |
| 14/08/2010 | Stockport | 0 | 0 | Wycombe | M Brown |
| 21/08/2010 | Stevenage | 3 | 1 | Stockport | R Lewis |
| 28/08/2010 | Stockport | 0 | 4 | Shrewsbury | P Quinn |
| 04/09/2010 | Macclesfield | 0 | 2 | Stockport | D Foster |
| 11/09/2010 | Stockport | 1 | 1 | Bradford | N Swarbrick |
| 18/09/2010 | Oxford | 0 | 1 | Stockport | C Boyeson |
| 25/09/2010 | Stockport | 2 | 2 | Aldershot | E Ilderton |
| 28/09/2010 | Stockport | 2 | 2 | Accrington | A Haines |
| 02/10/2010 | Burton | 2 | 1 | Stockport | A Woolmer |
| 09/10/2010 | Gillingham | 2 | 1 | Stockport | G Horwood |
| 16/10/2010 | Stockport | 2 | 1 | Barnet | A Bates |
| 23/10/2010 | Lincoln | 0 | 0 | Stockport | R Madley |
| 30/10/2010 | Stockport | 0 | 5 | Hereford | D Drysdale |
| 02/11/2010 | Morecambe | 5 | 0 | Stockport | G Eltringham |
| 13/11/2010 | Bury | 0 | 1 | Stockport | D Webb |
| 20/11/2010 | Stockport | 1 | 1 | Torquay | G Sutton |
| 23/11/2010 | Stockport | 0 | 5 | Port Vale | C Webster |
| 04/12/2010 | Northampton | 2 | 0 | Stockport | J Moss |
| 11/12/2010 | Stockport | 3 | 3 | Crewe | S Attwell |
| 28/12/2010 | Barnet | 1 | 3 | Stockport | G Horwood |
| 01/01/2011 | Chesterfield | 4 | 1 | Stockport | T Kettle |
| 03/01/2011 | Stockport | 0 | 2 | Morecambe | K Evans |
| 08/01/2011 | Stockport | 1 | 5 | Gillingham | C Webster |
| 11/01/2011 | Stockport | 3 | 3 | Rotherham | D Coote |
| 15/01/2011 | Hereford | 3 | 0 | Stockport | D Sheldrake |
| 22/01/2011 | Stockport | 3 | 4 | Lincoln | S Rushton |
| 29/01/2011 | Rotherham | 4 | 0 | Stockport | K Wright |
| 01/02/2011 | Stockport | 1 | 1 | Chesterfield | M Naylor |
| 05/02/2011 | Torquay | 2 | 0 | Stockport | S Hooper |
| 12/02/2011 | Stockport | 2 | 1 | Bury | D McDermid |
| 19/02/2011 | Stockport | 1 | 4 | Macclesfield | C Boyeson |
| 26/02/2011 | Bradford | 3 | 2 | Stockport | T Kettle |
| 01/03/2011 | Cheltenham | 2 | 1 | Stockport | R Booth |
| 05/03/2011 | Stockport | 2 | 1 | Oxford | R Shoebridge |
| 08/03/2011 | Accrington | 3 | 0 | Stockport | O Langford |
| 12/03/2011 | Stockport | 0 | 0 | Burton | G Salisbury |
| 19/03/2011 | Aldershot | 1 | 0 | Stockport | S Rushton |
| 26/03/2011 | Stockport | 2 | 1 | Southend | C Pawson |
| 02/04/2011 | Wycombe | 2 | 0 | Stockport | G Ward |
| 09/04/2011 | Stockport | 2 | 2 | Stevenage | G Eltringham |
| 16/04/2011 | Shrewsbury | 2 | 0 | Stockport | S Hooper |
| 23/04/2011 | Port Vale | 1 | 2 | Stockport | P Quinn |
| 25/04/2011 | Stockport | 2 | 2 | Northampton | N Miller |
| 30/04/2011 | Crewe | 2 | 0 | Stockport | A Bates |
| 07/05/2011 | Stockport | 1 | 1 | Cheltenham | D Phillips |