Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 07/08/2010 | Rotherham | 2 | 1 | Lincoln | R Shoebridge |
| 14/08/2010 | Lincoln | 0 | 2 | Torquay | M Naylor |
| 21/08/2010 | Gillingham | 0 | 1 | Lincoln | B Malone |
| 28/08/2010 | Lincoln | 1 | 1 | Crewe | D Foster |
| 04/09/2010 | Chesterfield | 2 | 1 | Lincoln | M Russell |
| 11/09/2010 | Lincoln | 1 | 0 | Barnet | P Quinn |
| 17/09/2010 | Accrington | 3 | 0 | Lincoln | A Bates |
| 25/09/2010 | Lincoln | 0 | 1 | Stevenage | K Wright |
| 28/09/2010 | Lincoln | 0 | 0 | Burton | P Miller |
| 02/10/2010 | Southend | 1 | 0 | Lincoln | D Sheldrake |
| 09/10/2010 | Lincoln | 2 | 1 | Macclesfield | D Webb |
| 16/10/2010 | Shrewsbury | 2 | 0 | Lincoln | P Gibbs |
| 23/10/2010 | Lincoln | 0 | 0 | Stockport | R Madley |
| 30/10/2010 | Wycombe | 2 | 2 | Lincoln | C Sarginson |
| 02/11/2010 | Lincoln | 0 | 2 | Northampton | M Brown |
| 13/11/2010 | Morecambe | 1 | 2 | Lincoln | N Miller |
| 20/11/2010 | Lincoln | 3 | 1 | Hereford | E Ilderton |
| 23/11/2010 | Lincoln | 0 | 5 | Bury | S Rushton |
| 01/01/2011 | Lincoln | 1 | 2 | Bradford | M Brown |
| 03/01/2011 | Northampton | 2 | 1 | Lincoln | G Hegley |
| 15/01/2011 | Lincoln | 1 | 2 | Wycombe | G Salisbury |
| 22/01/2011 | Stockport | 3 | 4 | Lincoln | S Rushton |
| 25/01/2011 | Cheltenham | 1 | 2 | Lincoln | A Taylor |
| 29/01/2011 | Lincoln | 1 | 0 | Port Vale | A Woolmer |
| 01/02/2011 | Bradford | 1 | 2 | Lincoln | A Haines |
| 05/02/2011 | Hereford | 0 | 1 | Lincoln | R Madley |
| 08/02/2011 | Lincoln | 1 | 5 | Shrewsbury | J Moss |
| 12/02/2011 | Lincoln | 2 | 0 | Morecambe | G Scott |
| 15/02/2011 | Aldershot | 2 | 2 | Lincoln | D Phillips |
| 19/02/2011 | Lincoln | 0 | 2 | Chesterfield | R Lewis |
| 26/02/2011 | Barnet | 4 | 2 | Lincoln | G Ward |
| 01/03/2011 | Lincoln | 3 | 1 | Oxford | G Eltringham |
| 05/03/2011 | Lincoln | 0 | 0 | Accrington | G Horwood |
| 08/03/2011 | Burton | 3 | 1 | Lincoln | M Haywood |
| 12/03/2011 | Lincoln | 2 | 1 | Southend | P Quinn |
| 15/03/2011 | Macclesfield | 1 | 1 | Lincoln | C Sarginson |
| 19/03/2011 | Stevenage | 2 | 1 | Lincoln | O Langford |
| 25/03/2011 | Lincoln | 0 | 6 | Rotherham | M Russell |
| 29/03/2011 | Port Vale | 2 | 1 | Lincoln | R Booth |
| 02/04/2011 | Torquay | 2 | 0 | Lincoln | I Williamson |
| 09/04/2011 | Lincoln | 0 | 4 | Gillingham | A Haines |
| 16/04/2011 | Crewe | 1 | 1 | Lincoln | P Miller |
| 22/04/2011 | Bury | 1 | 0 | Lincoln | T Kettle |
| 25/04/2011 | Lincoln | 0 | 2 | Cheltenham | K Evans |
| 30/04/2011 | Oxford | 2 | 1 | Lincoln | B Malone |
| 07/05/2011 | Lincoln | 0 | 3 | Aldershot | J Moss |