Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 08/08/2010 | Cardiff | 1 | 1 | Sheffield United | P Walton |
| 14/08/2010 | Derby | 1 | 2 | Cardiff | N Miller |
| 21/08/2010 | Cardiff | 4 | 0 | Doncaster | N Swarbrick |
| 28/08/2010 | Portsmouth | 0 | 2 | Cardiff | A Penn |
| 11/09/2010 | Cardiff | 2 | 0 | Hull | O Langford |
| 14/09/2010 | Leicester | 2 | 1 | Cardiff | K Evans |
| 18/09/2010 | Ipswich | 2 | 0 | Cardiff | F Graham |
| 25/09/2010 | Cardiff | 2 | 1 | Millwall | L Mason |
| 28/09/2010 | Cardiff | 0 | 0 | Crystal Palace | S Tanner |
| 02/10/2010 | Barnsley | 1 | 2 | Cardiff | T Kettle |
| 16/10/2010 | Cardiff | 3 | 2 | Bristol City | J Moss |
| 19/10/2010 | Coventry | 1 | 2 | Cardiff | J Linington |
| 25/10/2010 | Leeds | 0 | 4 | Cardiff | M Oliver |
| 30/10/2010 | Cardiff | 3 | 1 | Norwich | G Scott |
| 07/11/2010 | Cardiff | 0 | 1 | Swansea | M Jones |
| 10/11/2010 | Reading | 1 | 1 | Cardiff | A D'Urso |
| 13/11/2010 | Scunthorpe | 2 | 4 | Cardiff | E Ilderton |
| 20/11/2010 | Cardiff | 0 | 2 | Nott'm Forest | C Webster |
| 27/11/2010 | QPR | 2 | 1 | Cardiff | K Friend |
| 04/12/2010 | Cardiff | 1 | 1 | Preston | D Deadman |
| 11/12/2010 | Middlesbrough | 1 | 0 | Cardiff | A Bates |
| 26/12/2010 | Cardiff | 2 | 0 | Coventry | G Salisbury |
| 28/12/2010 | Watford | 4 | 1 | Cardiff | M Haywood |
| 01/01/2011 | Bristol City | 3 | 0 | Cardiff | S Attwell |
| 04/01/2011 | Cardiff | 2 | 1 | Leeds | A D'Urso |
| 15/01/2011 | Norwich | 1 | 1 | Cardiff | K Stroud |
| 22/01/2011 | Cardiff | 4 | 2 | Watford | S Tanner |
| 01/02/2011 | Cardiff | 2 | 2 | Reading | G Ward |
| 06/02/2011 | Swansea | 0 | 1 | Cardiff | M Halsey |
| 12/02/2011 | Cardiff | 1 | 0 | Scunthorpe | P Crossley |
| 15/02/2011 | Cardiff | 1 | 1 | Burnley | R East |
| 19/02/2011 | Nott'm Forest | 2 | 1 | Cardiff | J Moss |
| 22/02/2011 | Cardiff | 2 | 0 | Leicester | D McDermid |
| 26/02/2011 | Hull | 0 | 2 | Cardiff | P Tierney |
| 05/03/2011 | Cardiff | 0 | 2 | Ipswich | A Bates |
| 08/03/2011 | Crystal Palace | 1 | 0 | Cardiff | M Russell |
| 13/03/2011 | Cardiff | 2 | 2 | Barnsley | R Booth |
| 19/03/2011 | Millwall | 3 | 3 | Cardiff | A Taylor |
| 02/04/2011 | Cardiff | 4 | 1 | Derby | J Linington |
| 09/04/2011 | Doncaster | 1 | 3 | Cardiff | S Hooper |
| 12/04/2011 | Sheffield United | 0 | 2 | Cardiff | M Oliver |
| 16/04/2011 | Cardiff | 3 | 0 | Portsmouth | K Wright |
| 23/04/2011 | Cardiff | 2 | 2 | QPR | L Mason |
| 25/04/2011 | Preston | 0 | 1 | Cardiff | P Gibbs |
| 02/05/2011 | Cardiff | 0 | 3 | Middlesbrough | G Scott |
| 07/05/2011 | Burnley | 1 | 1 | Cardiff | C Webster |